The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2021
Filed:
Oct. 01, 2020
Applicant:
Immunicom, Inc., San Diego, CA (US);
Inventors:
Steven Josephs, San Diego, CA (US);
Matthew Ong, San Diego, CA (US);
Amir Jafri, San Diego, CA (US);
Robert Segal, San Diego, CA (US);
Stephen Prince, San Diego, CA (US);
Assignee:
IMMUNICOM, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2006.01); G01N 33/543 (2006.01); C07K 14/525 (2006.01); G01N 33/68 (2006.01); A61M 1/34 (2006.01);
U.S. Cl.
CPC ...
A61M 1/362 (2014.02); A61M 1/3496 (2013.01); A61M 1/36 (2013.01); C07K 14/525 (2013.01); G01N 33/54313 (2013.01); G01N 33/54366 (2013.01); G01N 33/6863 (2013.01); A61M 2202/0415 (2013.01); G01N 2333/70578 (2013.01);
Abstract
The present system and method are useful for the removal of immune inhibitors such as soluble TNF receptors from the body fluid of cancer patients. In some embodiments, soluble TNF-Receptors 1 and 2 are selectively removed from plasma at 80% or more efficiency. In some embodiments, the system includes an immobilized capture ligand of a single chain TNFα. The system and method are useful for the treatment of different cancer types, stages and severity.