The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Jan. 22, 2020
Applicant:
China Medical University, Taichung, TW;
Inventors:
Ching-Shih Chen, Taichung, TW;
Hsiang-Wen Lin, Taichung, TW;
Chih-Shiang Chang, Taichung, TW;
Po-Chen Chu, Taichung, TW;
Assignee:
CHINA MEDICAL UNIVERSITY, Taichung, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/06 (2006.01); C07D 231/12 (2006.01); C07D 207/337 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 413/06 (2013.01); A61P 35/00 (2018.01); C07D 207/337 (2013.01); C07D 231/12 (2013.01);
Abstract
The invention provides a novel class of propiolylamide-based irreversible inhibitors of PKM2 compounds of the general formula I, pharmaceutical compositions, and methods of inducing an anti-tumor effect in a subject suffering from tumor comprising administering to the subject a pharmaceutical composition comprising an effective amount of compound of formula I.