The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2021
Filed:
Mar. 15, 2019
Applicant:
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Thomas Brennan, Cupertino, CA (US);
David Bellovin, San Jose, CA (US);
David Busha, Sausalito, CA (US);
Barbara Sennino, San Francisco, CA (US);
Assignee:
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70532 (2013.01); A61K 38/1774 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/00 (2013.01); C07K 16/2803 (2013.01); A61K 38/00 (2013.01); C07K 2317/41 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01);
Abstract
This application relates to CD80 (B7-1) extracellular domain (ECD) polypeptides and CD80-ECD fusion molecules and their use in treatment of cancer, both alone and in combination with other therapeutic agents, such as immune stimulating agents such as PD-1/PD-L1 inhibitors.