The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2021
Filed:
Dec. 14, 2016
Applicants:
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Stoke Therapeutics, Inc., Bedford, MA (US);
Inventors:
Isabel Aznarez, Cambridge, MA (US);
Huw M. Nash, Lexington, MA (US);
Adrian Krainer, East Northport, NY (US);
Assignees:
COLD SPRING HARBOR LABORATORY, Cold Spring Harbor, NY (US);
STOKE THERAPEUTICS, INC., Bedford, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/7125 (2006.01); A61K 31/712 (2006.01); C12Q 1/6883 (2018.01); C12N 15/113 (2010.01); C12Q 1/68 (2018.01); A61K 31/713 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7125 (2013.01); A61K 31/712 (2013.01); A61K 31/713 (2013.01); A61P 43/00 (2018.01); C12N 15/1138 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6883 (2013.01); A61K 2300/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/346 (2013.01); C12N 2320/33 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Provided herein are methods and compositions for treating a subject in need thereof, such as a subject with deficient SYNGAP1 protein or SCN1A protein expression or a subject having AD mental retardation 5 or Dravet syndrome.