The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 2021
Filed:
Mar. 27, 2018
Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);
Craig Alan Aspinwall, Tuscon, AZ (US);
Steven Scott Saavedra, Tuscon, AZ (US);
Mark Tadashi Agasid, Tuscon, AZ (US);
Arizona Board of Regents on Behalf of the University Of Arizona, Tuscon, AZ (US);
Abstract
Ligand-ion channel interactions are analyzed via electrophysiological methods having rapid temporal response and high sensitivity, thereby reducing the collection time and enabling monitoring of dynamic processes. This protocol allows quantification of ligand concentrations in the sub-millisecond to ms range, as compared to s-min for traditional approaches. Moreover, the method can be easily integrated into existing patch clamp analysis packages and allow for monitoring of rapid, dynamic chemical processes in a feasible manner.