The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2021
Filed:
Aug. 05, 2019
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2020.01); C12N 15/63 (2006.01); C12N 15/64 (2006.01); A01K 67/027 (2006.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01); C12N 7/00 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01); C07H 21/04 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); A01K 67/0273 (2013.01); A01K 67/0276 (2013.01); C12N 7/00 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/1132 (2013.01); C12N 15/63 (2013.01); C12N 15/85 (2013.01); C12N 15/8509 (2013.01); C12N 15/907 (2013.01); A01K 2207/05 (2013.01); A01K 2207/10 (2013.01); A01K 2227/108 (2013.01); A01K 2267/025 (2013.01); C07H 21/02 (2013.01); C07H 21/04 (2013.01); C12N 2310/20 (2017.05); C12N 2740/10062 (2013.01); C12N 2800/80 (2013.01);
Abstract
A method of modulating some or all copies of a gene in a cell is provided including introducing into a cell one or more ribonucleic acid (RNA) sequences that comprise a portion that is complementary to all or a portion of each of the one or more target nucleic acid sequences, and a nucleic acid sequence that encodes a Cas protein and maintaining the cells under conditions in which the Cas protein is expressed and the Cas protein binds and modulates the one or more target nucleic acid sequences in the cell.