The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Jul. 14, 2017
Applicant:

Genomatica, Inc., San Diego, CA (US);

Inventors:

Derek L. Greenfield, South San Francisco, CA (US);

Andreas W. Schirmer, South San Francisco, CA (US);

Elizabeth J. Clarke, South San Francisco, CA (US);

Eli S. Groban, South San Francisco, CA (US);

Bernardo M. Da Costa, South San Francisco, CA (US);

Zhihao Hu, South San Francisco, CA (US);

Kevin Holden, South San Francisco, CA (US);

Noah Helman, South San Francisco, CA (US);

Assignee:

Genomatica, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01); C12P 7/64 (2006.01); C07K 14/195 (2006.01); C07K 14/245 (2006.01); C12N 9/16 (2006.01); C12N 15/70 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 9/00 (2006.01); C12P 7/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C12N 9/001 (2013.01); C12N 9/0006 (2013.01); C12N 9/1029 (2013.01); C12N 9/1288 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 9/93 (2013.01); C12P 7/04 (2013.01); C12P 7/6409 (2013.01); C12P 7/6436 (2013.01); C12Y 101/011 (2013.01); C12Y 103/0101 (2013.01); C12Y 103/01009 (2013.01); C12Y 203/0118 (2013.01); C12Y 203/01039 (2013.01); C12Y 203/01041 (2013.01); C12Y 203/01179 (2013.01); C12Y 207/08007 (2013.01); C12Y 402/01059 (2013.01); C12Y 503/03014 (2013.01); C12Y 604/01002 (2013.01);
Abstract

The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell.


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