The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Mar. 27, 2019
Applicant:
Alan Marc Kleinfeld, La Jolla, CA (US);
Inventors:
Alan Marc Kleinfeld, La Jolla, CA (US);
Andrew Henry Huber, Encinitas, CA (US);
James Patrick Kampf, San Diego, CA (US);
Thomas Kwan, San Diego, CA (US);
Baolong Zhu, San Diego, CA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/533 (2006.01); G01N 33/72 (2006.01); C07K 14/47 (2006.01); G01N 33/92 (2006.01); G01N 21/64 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/728 (2013.01); C07K 14/47 (2013.01); G01N 21/6428 (2013.01); G01N 33/533 (2013.01); G01N 33/582 (2013.01); G01N 33/92 (2013.01); G01N 2800/52 (2013.01); Y10T 436/146666 (2015.01);
Abstract
Identification and use of proteins fluorescently labeled and that undergo a change in fluorescence index upon binding bilirubin are described. Probes are disclosed which are labeled at a cysteine or lysine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for determination of unbound bilirubin levels in a fluid sample.