The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2021
Filed:
Apr. 18, 2016
Amgen Research (Munich) Gmbh, Munich, DE;
Bertram Weiss, Berlin, DE;
Ann-Lena Frisk, Berlin, DE;
Ruprecht Zierz, Berlin, DE;
Peter Kufer, Munich, DE;
Tobias Raum, Munich, DE;
Doris Rau, Munich, DE;
Jonas Anlahr, Munich, DE;
Ralf Lutterbüse, Munich, DE;
Lisa Nahrwold, Munich, DE;
Christoph Dahlhoff, Munich, DE;
Claudia Blümel, Munich, DE;
Patrick Hoffmann, Munich, DE;
AMGEN RESEARCH (MUNICH) GMBH, Munich, DE;
Abstract
The present invention relates to a bispecific antibody construct comprising a first human binding domain which binds to human CDH3 on the surface of a target cell and a second binding domain which binds to human CDS on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.