The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Sep. 23, 2019
Applicant:

Gen9, Inc., Boston, MA (US);

Inventors:

Joseph Jacobson, Newton, MA (US);

Michael E. Hudson, Framingham, MA (US);

Larry Li-Yang Chu, Cambridge, MA (US);

Assignee:

Gen9, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); B01J 19/00 (2006.01); C40B 50/14 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1086 (2013.01); B01J 19/0046 (2013.01); C40B 50/14 (2013.01); B01J 2219/00378 (2013.01); B01J 2219/00509 (2013.01); B01J 2219/00531 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00621 (2013.01); B01J 2219/00644 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00725 (2013.01);
Abstract

Methods and devices are provided for preparing a protein array having a plurality of proteins. In one embodiment, the method includes providing a plurality of nucleic acids each having a predefined sequence and expressing in vitro a plurality of proteins from the plurality of nucleic acids. In another embodiment, protein arrays having a solid surface and a microvolume are also provided. The solid surface can have a plurality of anchor oligonucleotides capable of hybridizing with a plurality of nucleic acids. The microvolume can cover each of the plurality of anchor oligonucleotides and can be configured to produce a polypeptide from each of the plurality of nucleic acids.


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