The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Sep. 18, 2018
Zhejiang Gongshang University, Hangzhou, CN;
Rongcheng Huatong Marine Biotechnology Co. Ltd, Rongcheng, CN;
Yanbo Wang, Hangzhou, CN;
Linglin Fu, Hangzhou, CN;
Zhongfu Liu, Rongcheng, CN;
Feifei Wang, Hangzhou, CN;
Fan Li, Hangzhou, CN;
Junbo Liang, Rongcheng, CN;
ZHEJIANG GONGSHANG UNIVERSITY, Hangzhou, CN;
RONGCHENG HUATONG MARINE BIOTECHNOLOGY CO. LTD., Rongcheng, CN;
Abstract
The present invention provides a PEG-ACS/M-siRNA nanocomposite application, and method for reducing the histamine content during fishmeal storage thereof. A small interfering ribonucleic acid (siRNA) is designed and prepared according to a histidine decarboxylase gene of(subsp.KT), and the histidine decarboxylase gene has a sequence of SEQ ID No: 1. A PEG-ACS/M-siRNA nanocomposite is prepared by using a PEGylated arginine-modified chitosan as a carrier. A PEG-ACS/M-siRNA nanocomposite is added to fishmeal in a certain ratio. The method for reducing the histamine content during fishmeal storage has a significant inhibitory effect on the histamine content during fishmeal storage, and can reduce the histamine content in fishmeal by 49%-53%, which has great significance for the control of biogenic amines in fishmeal in the feed industry.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile