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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10961269 B1

PDFFull Text
Date of Patent:
Mar. 30, 2021

Filed:

Sep. 20, 2016

Bridged nucleic acid guna, method for producing same, and intermediate compound

Applicants:

Mitsubishi Tanabe Pharma Corporation, Osaka, JP;

Osaka University, Suita, JP;

Inventors:

Satoshi Obika, Minoo, JP;

Eiji Kawanishi, Osaka, JP;

Hiroaki Sawamoto, Osaka, JP;

Shuhei Yamakoshi, Osaka, JP;

Yuuki Aral, Osaka, JP;

Shinji Kumagai, Osaka, JP;

Assignees:

MITSUBISHI TANABE PHARMA CORPORATION, Osaka, JP;

OSAKA UNIVERSITY, Suita, JP;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Lawrence E Crane

Int. Cl.
CPC ...
C07H 19/06 (2006.01); C07H 9/06 (2006.01); C07H 21/00 (2006.01); C07H 19/16 (2006.01); C07H 1/00 (2006.01); C07C 279/16 (2006.01); C07D 498/04 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07H 19/06 (2013.01); C07H 1/00 (2013.01); C07H 9/06 (2013.01); C07H 19/16 (2013.01); C07H 21/00 (2013.01); C07C 279/16 (2013.01); C07D 498/04 (2013.01); C07D 498/08 (2013.01);
Abstract

A method for preparing a compound represented by general formula I: or a salt thereof includes a step of reacting a compound represented by formula II: with a reducing agent to cleave an oxazolidine ring fused to a cycle A'. The reducing agent includes at least one of phosphines, metal hydrides, or transition metal catalysts in the presence of hydrogen gas.

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Obika, Satoshi. (2021). Bridged nucleic acid guna, method for producing same, and intermediate compound (U.S. Patent No. 10961269). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10961269

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