The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2021
Filed:
Oct. 10, 2019
Applicant:
New England Biolabs, Inc., Ipswich, MA (US);
Inventors:
Jennifer Ong, Salem, MA (US);
Nathan Tanner, West Newbury, MA (US);
Yinhua Zhang, North Reading, MA (US);
Yanxia Bei, Ipswich, MA (US);
Vladimir Potapov, Auburndale, MA (US);
Assignee:
New England Biolabs, Inc., Ipswich, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1252 (2013.01); C12N 7/00 (2013.01); C12Y 207/07007 (2013.01);
Abstract
Variants of the bacteriophage B103 DNA polymerase are described herein. The variant has improved properties, that include when compared to wild-type Phi29 DNA polymerase, at least one of the following: increased thermostability, improved reaction rate for DNA amplification, reduced background and a reduction of bias. Methods of using the DNA polymerase variant are also described herein.