The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Nov. 30, 2016
Applicant:
Concordia University, Inc., Mequon, WI (US);
Inventors:
Joseph McGraw, Germantown, WI (US);
Armin Gerhardt, Mettawa, IL (US);
Assignee:
Concordia University Inc., Mequon, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/26 (2006.01); G01N 33/74 (2006.01); A61K 9/46 (2006.01); A61K 9/20 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/26 (2013.01); G01N 33/743 (2013.01); A61K 9/0007 (2013.01); A61K 9/0056 (2013.01); A61K 9/2054 (2013.01); G01N 2333/90241 (2013.01);
Abstract
Disclosed are methods and compositions which may be used in human cytochrome P450 (CYP450) enzyme phenotyping. The methods and compositions typically utilize a mélange of substrates for different CYP450 enzymes which may be administered orally to a patient. Subsequently, the metabolites of the substrates may be detected in the patient's saliva as well as any non-metabolized substrates to calculate a metabolic ratio for any given CYP450 enzyme in order to generate a phenotypic CYP450 enzyme profile for the patient.