The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2021

Filed:

Nov. 03, 2014
Applicant:

Washington University, St. Louis, MO (US);

Inventors:

Jeffrey I. Gordon, St. Louis, MO (US);

Sathish Subramanian, St. Louis, MO (US);

Ansel Hsiao, St. Louis, MO (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); C12Q 1/689 (2018.01); C12Q 1/10 (2006.01); G06G 7/58 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); C12Q 1/10 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/06 (2013.01);
Abstract

The present invention provides a method to define normal maturation of the gut microbiota using a limited number of bacterial taxa found in the gut microbiota. Regressing the relative abundance of age-discriminatory taxa in their gut microbiota against the chronological age of each healthy subject at the time a sample of the gut microbiota was collected produces a regression model that may be used to characterize the maturity of another subject's gut microbiota to provide a measure of gastrointestinal health without having to query the whole microbiota. The present invention also provides composition and methods for preventing and/or treating a disease in a subject in need thereof.


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