The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Mar. 23, 2012
Arick Brown, Pacifica, CA (US);
Junyan Ji, South San Francisco, CA (US);
Jun Liu, Pacifica, CA (US);
Yuchang John Wang, South San Francisco, CA (US);
Arick Brown, Pacifica, CA (US);
Junyan Ji, South San Francisco, CA (US);
Jun Liu, Pacifica, CA (US);
Yuchang John Wang, South San Francisco, CA (US);
GENENTECH, INC., South San Francisco, CA (US);
Abstract
The invention provides methods of reducing fouling of ultrafiltration membranes in processes wherein virus particles are removed from aqueous solutions comprising virus particles and at least one protein by adding a surfactant or non-surfactant, non-ionic agent to the aqueous solution prior to filtration. The invention also provides methods to dissociate protein aggregates or to reduce the formation of protein aggregates by adding a surfactant or non-surfactant, non-ionic agent to the protein solution.