The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Jun. 03, 2019
Applicant:
Bruker Daltonik Gmbh, Bremen, DE;
Inventors:
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); H01J 49/00 (2006.01); H01J 49/16 (2006.01); H01J 49/40 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6851 (2013.01); G01N 33/94 (2013.01); H01J 49/0027 (2013.01); H01J 49/164 (2013.01); H01J 49/40 (2013.01); G01N 2440/38 (2013.01); G01N 2560/00 (2013.01);
Abstract
The invention provides methods for characterizing a target protein wherein a mass spectrum of digest peptides of the target protein is acquired and compared with measured reference mass spectra of digest peptides of reference proteins or of proteins of reference host cells. The comparison comprises determining similarity scores of the intensity patterns of the mass spectrum and the reference mass spectra. The characterization comprises assigning the target protein to a reference protein having a reference mass spectrum with a similarity score above a predetermined threshold.