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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10874625 B1

PDFFull Text
Date of Patent:
Dec. 29, 2020

Filed:

Oct. 08, 2018

Methods for the biosynthesis of taurine or hypotaurine in cells

Applicant:

Plant Sensory Systems Llc, Baltimore, MD (US);

Inventors:

Frank J. Turano, Baltimore, MD (US);

Kathleen A. Turano, Baltimore, MD (US);

Peter S. Carlson, Baltimore, MD (US);

Alan M. Kinnersley, Baltimore, MD (US);

Assignee:

PLANT SENSORY SYSTEMS, LLC, Baltimore, MD (US);

Attorney:

Rothwell, Figg, Ernst & Manbeck, P.C.

Primary Examiner:

Russell Kallis

Int. Cl.
CPC ...
C12N 15/70 (2006.01); A61K 31/145 (2006.01); C12N 15/82 (2006.01); A61K 31/185 (2006.01); A23K 20/10 (2016.01); A23K 10/12 (2016.01); C12N 9/02 (2006.01); C12P 13/00 (2006.01); A23L 33/10 (2016.01); A23L 33/175 (2016.01); C12P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/145 (2013.01); A23K 10/12 (2016.05); A23K 20/10 (2016.05); A23L 33/10 (2016.08); A23L 33/175 (2016.08); A61K 31/185 (2013.01); C12N 9/0069 (2013.01); C12N 15/8243 (2013.01); C12N 15/8251 (2013.01); C12N 15/8253 (2013.01); C12N 15/8261 (2013.01); C12N 15/8271 (2013.01); C12N 15/8273 (2013.01); C12N 15/8279 (2013.01); C12P 11/00 (2013.01); C12P 13/001 (2013.01); A23V 2002/00 (2013.01); C12Y 113/1102 (2013.01); Y02A 40/146 (2018.01); Y02A 50/30 (2018.01);
Abstract

The present invention describes an approach to increase taurine or hypotaurine production in prokaryotes. More particularly, the invention relates to genetic transformation of organisms with genes that encode proteins that catalyze the conversion of cysteine to taurine, methionine to taurine, cysteamine to taurine, or alanine to taurine. The invention describes methods for the use of polynucleotides that encode cysteine dioxygenase (CDO) and sulfinoalanine decarboxylase (SAD) polypeptides in prokaryotes to increase taurine, hypotaurine or taurine precursor production. The preferred embodiment of the invention is in plants but other organisms may be used. Increased taurine production in prokaryotes could be used as nutraceutical, pharmaceutical, or therapeutic compounds or as a supplement in animal feed.

Find Patent Forward Citations

Turano, Frank. (2020). Methods for the biosynthesis of taurine or hypotaurine in cells (U.S. Patent No. 10874625). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10874625

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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