The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2020
Filed:
Oct. 30, 2017
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Brendan M. Crowley, Collegeville, PA (US);
Ian M. Bell, Harleysville, PA (US);
Andrew John Harvey, Paddington, AU;
William D. Shipe, Chalfont, PA (US);
Kenneth J. Leavitt, Mount Laurel, NJ (US);
John M. Sanders, Hatfield, PA (US);
Deodial G. Guiadeen, Chesterfield, NJ (US);
Linda M. Suen, Philadelphia, PA (US);
Thomas J. Greshock, Collegeville, PA (US);
Vanessa L. Rada, Hatfield, PA (US);
Abstract
The present disclosure relates to compounds of formula (I) that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation.