The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2020

Filed:

Sep. 20, 2017
Applicants:

Kristen Naegle, St. Louis, MO (US);

Roman Sloutsky, St. Louis, MO (US);

Inventors:

Kristen Naegle, St. Louis, MO (US);

Roman Sloutsky, St. Louis, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12P 21/04 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01); C07K 14/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/12 (2013.01); C12P 21/00 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present disclosure provides a system to produce soluble, folded, and post-translationally modified proteins. The system includes a fusion protein comprising a catalytic domain of an enzyme involved in post-translational protein modification and a targeting domain, and a substrate protein comprising a protein of interest and a sequence that interacts with the targeting domain. The present disclosure also provides polynucleotide sequences encoding fusion proteins and substrate proteins, vectors for expressing polynucleotide sequences, vectors comprising the polynucleotide sequences, and isolated cells comprising said vectors.


Find Patent Forward Citations

Naegle, Kristen. (2020). Toolkit for the production of post-translationally modified proteins (U.S. Patent No. 10865394). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10865394

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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