The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Sep. 19, 2017
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Yong-Su Jin, Champaign, IL (US);

Stephan Thomas Lane, Bloomington, IL (US);

Haiqing Xu, Ann Arbor, MI (US);

Soo-Rin Kim, Daegu, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); C12N 1/26 (2006.01); C12N 9/12 (2006.01); C12P 7/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); C12N 1/26 (2013.01); C12N 9/1258 (2013.01); C12P 7/06 (2013.01);
Abstract

The present disclosure provides recombinant microorganisms capable of sugar co-utilization, the recombinant microorganism comprising a genetically altered microorganism (e.g.) having a lack of, or reduced expression of, or expression of truncated or mutated forms of at least one polypeptide selected from Hxk1, Hxk2, and Glk1. Reduction of the expression or biological activity of Hxk1, Hxk2 and Glk1 leads to reduction in the glucose consumption pathway, allowing the microorganism to co-utilize multiple sugars (e.g. glucose, xylose, galactose) at an improved rate.


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