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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10836767 B1

PDFFull Text
Date of Patent:
Nov. 17, 2020

Filed:

Jun. 29, 2018

Serum stable pro-coelenterazine analogues

Applicant:

Promega Corporation, Madison, WI (US);

Inventors:

Wenhui Zhou, San Luis Obispo, CA (US);

Brock Binkowski, Sauk City, WI (US);

Poncho Meisenheimer, San Luis Obispo, CA (US);

Andrew L. Niles, Madison, WI (US);

Kevin Kupcho, Madison, WI (US);

James Unch, Arroyo Grande, CA (US);

Assignee:

PROMEGA CORPORATION, Madison, WI (US);

Attorneys:

Casimir Jones, S.C.

Anne M. Reynolds

Primary Examiner:

Susan M Hanley

Int. Cl.
CPC ...
C07D 487/04 (2006.01); G01N 33/58 (2006.01); C12Q 1/66 (2006.01); G01N 21/76 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C12Q 1/66 (2013.01); G01N 33/582 (2013.01); G01N 21/763 (2013.01); G01N 2333/90241 (2013.01); G01N 2333/916 (2013.01);
Abstract

Described are pro-coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays or fragment complementary luciferase. The disclosed pro-coelenterazine analogues provide increased serum stability for live cell assays, and are capable of tuning the brightness and assay windows as needed for the applications.

Find Patent Forward Citations

Zhou, Wenhui. (2020). Serum stable pro-coelenterazine analogues (U.S. Patent No. 10836767). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10836767

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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