The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Nov. 07, 2017
Applicant:
Arcturus Therapeutics, Inc., San Diego, CA (US);
Inventors:
Padmanabh Chivukula, San Diego, CA (US);
Luigi Warren, San Diego, CA (US);
Kiyoshi Tachikawa, San Diego, CA (US);
Joseph E. Payne, San Diego, CA (US);
Assignee:
ARCTURUS THERAPEUTICS, INC., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 9/10 (2006.01); C07K 14/46 (2006.01); C07K 14/47 (2006.01); C07K 14/505 (2006.01); C07K 14/52 (2006.01); C07K 14/575 (2006.01); C07K 14/705 (2006.01); C07K 14/745 (2006.01); C07K 14/805 (2006.01); C07K 14/81 (2006.01); C12N 9/02 (2006.01); C12N 9/12 (2006.01); C12N 9/44 (2006.01); C12N 9/64 (2006.01); C12N 9/88 (2006.01); C07K 14/445 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1018 (2013.01); C07K 14/445 (2013.01); C07K 14/463 (2013.01); C07K 14/47 (2013.01); C07K 14/4712 (2013.01); C07K 14/4717 (2013.01); C07K 14/505 (2013.01); C07K 14/524 (2013.01); C07K 14/575 (2013.01); C07K 14/705 (2013.01); C07K 14/745 (2013.01); C07K 14/805 (2013.01); C07K 14/8125 (2013.01); C12N 9/0071 (2013.01); C12N 9/1051 (2013.01); C12N 9/1205 (2013.01); C12N 9/2451 (2013.01); C12N 9/644 (2013.01); C12N 9/88 (2013.01); C12Y 114/16001 (2013.01); C12Y 201/03003 (2013.01); C12Y 204/01025 (2013.01); C12Y 207/0104 (2013.01); C12Y 302/01033 (2013.01); C12Y 304/21022 (2013.01); C12Y 403/02001 (2013.01); A61K 39/00 (2013.01); A61K 48/00 (2013.01); C12N 2740/16222 (2013.01); C12N 2840/105 (2013.01); C12N 2840/60 (2013.01);
Abstract
This invention provides a range of translatable messenger UNA (mUNA) molecules. The mUNA molecules can be translated in vitro and in vivo to provide an active polypeptide or protein, or to provide an immunization agent or vaccine component. The mUNA molecules can be used as an active agent to express an active polypeptide or protein in cells or subjects. Among other things, the mUNA molecules are useful in methods for treating rare diseases.