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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10815197 B1

PDFFull Text
Date of Patent:
Oct. 27, 2020

Filed:

Jan. 24, 2017

N-sulfonyl benzamides as voltage-gated sodium channel inhibitors

Applicants:

Shanghai Haiyan Pharmaceutical Technology Co., Ltd., Shanghai, CN;

Yangtze River Pharmaceutical Group Co., Ltd., Jiangsu, CN;

Inventors:

Jiong Lan, Shanghai, CN;

Fusheng Zhou, Shanghai, CN;

Jinzhu Zhao, Shanghai, CN;

Dong Huang, Shanghai, CN;

Jing Xie, Shanghai, CN;

Yi Hu, Shanghai, CN;

Qiang Lv, Shanghai, CN;

Assignees:

SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., Shanghai, CN;

YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD., Shanghai, CN;

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo PC

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/166 (2006.01); C07C 233/64 (2006.01); C07D 207/09 (2006.01); C07D 401/04 (2006.01); C07D 211/46 (2006.01); C07D 295/155 (2006.01); A61K 31/4439 (2006.01); A61K 31/495 (2006.01); C07D 213/74 (2006.01); A61K 31/496 (2006.01); A61K 31/451 (2006.01); C07D 207/08 (2006.01); A61K 31/40 (2006.01); C07D 213/80 (2006.01); C07D 241/04 (2006.01);
U.S. Cl.
CPC ...
C07D 207/09 (2013.01); A61K 31/40 (2013.01); A61K 31/4439 (2013.01); A61K 31/451 (2013.01); A61K 31/495 (2013.01); A61K 31/496 (2013.01); C07D 207/08 (2013.01); C07D 211/46 (2013.01); C07D 213/74 (2013.01); C07D 213/80 (2013.01); C07D 241/04 (2013.01); C07D 295/155 (2013.01); C07D 401/04 (2013.01);
Abstract

The present invention discloses an N-sulfonyl benzamide derivative with a heterocyclic substituent, and a preparation method therefor and a pharmaceutical application thereof. More specifically, the invention discloses a compound represented by formula (II) or a pharmaceutically acceptable salt, stereoisomer, solvent compound, or prodrug thereof, and a preparation method therefor and an application thereof. Refer to the specification for definitions of each group in the formula.

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