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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10799543 B1

PDFFull Text
Date of Patent:
Oct. 13, 2020

Filed:

Jul. 09, 2019

Oncolytic poliovirus for human tumors

Applicant:

Duke University, Durham, NC (US);

Inventors:

Matthias Gromeier, Durham, NC (US);

John H. Sampson, Durham, NC (US);

Darell D. Bigner, Mebane, NC (US);

Annick Desjardins, Durham, NC (US);

Henry S. Friedman, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:

Banner & Witcoff, Ltd.

Primary Examiner:

Shanon A Foley

Assistant Examiner:

Myron G Hill

Int. Cl.
CPC ...
A61K 35/768 (2015.01); A61K 9/00 (2006.01); A61K 41/00 (2020.01); A61K 45/06 (2006.01); A61K 51/08 (2006.01); A61N 5/10 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 9/0085 (2013.01); A61K 41/00 (2013.01); A61K 45/06 (2013.01); A61K 51/081 (2013.01); A61N 5/10 (2013.01); C12N 7/00 (2013.01); C12N 2770/32611 (2013.01); C12N 2770/32632 (2013.01); C12N 2770/32671 (2013.01); C12N 2770/32733 (2013.01); Y02A 50/465 (2018.01);
Abstract

Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. The mechanism of action is believed to involve both viral oncolysis as well as immune recruitment, both of which lead to necrosis in the area of the tumor. No adverse effects have been observed.

Find Patent Forward Citations

Gromeier, Matthias. (2020). Oncolytic poliovirus for human tumors (U.S. Patent No. 10799543). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10799543

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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