The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Dec. 21, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Pei-Yu E. Chiou, Los Angeles, CA (US);

Michael A. Teitell, Tarzana, CA (US);

Ming-Yu Lin, Hsinchu County, TW;

Yi-Chien Wu, Taichung, TW;

Jessica Zhou, Chino, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B82Y 5/00 (2011.01); C12N 13/00 (2006.01); C12N 15/87 (2006.01); C12N 15/89 (2006.01);
U.S. Cl.
CPC ...
C12N 13/00 (2013.01); C12N 15/895 (2013.01);
Abstract

In various embodiments methods are provided for delivering an agent of interest (e.g., protein, antibody, nucleic acid) into cells. In certain embodiments the method comprises contacting the cells with anisotropic magnetic particles in the presence of the agent; and applying a substantially uniform magnetic field to said magnetic particles where movement of said particles induced by said magnetic field introduces transient openings into said cell facilitating entry of said agent of interest into said cells.


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