The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2020

Filed:

Jul. 24, 2017
Applicants:

Michael H. Baym, Cambridge, MA (US);

Bonnie Berger Leighton, Cambridge, MA (US);

Po-ru Loh, Cambridge, MA (US);

Inventors:

Michael H. Baym, Cambridge, MA (US);

Bonnie Berger Leighton, Cambridge, MA (US);

Po-Ru Loh, Cambridge, MA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 50/00 (2019.01); H03M 7/30 (2006.01);
U.S. Cl.
CPC ...
G16B 50/00 (2019.02); H03M 7/3062 (2013.01);
Abstract

The redundancy in genomic sequence data is exploited by compressing sequence data in such a way as to allow direct computation on the compressed data using methods that are referred to herein as 'compressive' algorithms. This approach reduces the task of computing on many similar genomes to only slightly more than that of operating on just one. In this approach, the redundancy among genomes is translated into computational acceleration by storing genomes in a compressed format that respects the structure of similarities and differences important to analysis. Specifically, these differences are the nucleotide substitutions, insertions, deletions, and rearrangements introduced by evolution. Once such a compressed library has been created, analysis is performed on it in time proportional to its compressed size, rather than having to reconstruct the full data set every time one wishes to query it.


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