The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Mar. 07, 2018
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

S. B. Jennifer Kan, Pasadena, CA (US);

Xiongyi Huang, Pasadena, CA (US);

Kai Chen, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/12 (2006.01); C12P 17/10 (2006.01); C12N 9/02 (2006.01); C07K 14/195 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0053 (2013.01); C07K 14/195 (2013.01); C12P 17/10 (2013.01); C12P 17/12 (2013.01); C12Y 109/03001 (2013.01);
Abstract

Provided herein are methods for producing an organoboron product. The methods include combining a boron-containing reagent and a carbene precursor in the presence of a heme protein, e.g., a cytochrome c, a cytochrome P450, a globin, a protoglobin, a nitric oxide dioxygenase, a peroxidase, or a catalase, or a variant thereof, under conditions sufficient to form the organoboron product. Reaction mixtures for producing organoboron products are also described, as well as whole-cell catalysts comprising heme proteins and variants thereof for forming carbon-boron bonds.


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