The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2020

Filed:

Jul. 15, 2019
Applicant:

Lts Lohmann Therapie-systeme Ag, Andernach, DE;

Inventors:

Michael Li, Martinsville, NJ (US);

Markus Krumme, Neuwied, DE;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A23L 27/00 (2016.01); A61K 36/47 (2006.01); A61K 31/192 (2006.01); A61K 47/18 (2017.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01); A61K 9/00 (2006.01); B29C 41/00 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01); A61K 47/46 (2006.01); B29B 7/88 (2006.01); B29B 13/00 (2006.01); B29C 39/02 (2006.01); B29C 39/36 (2006.01); B29C 39/38 (2006.01); B29C 69/00 (2006.01); B29K 105/00 (2006.01); B29L 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 36/47 (2013.01); A23L 27/88 (2016.08); A61K 9/006 (2013.01); A61K 31/192 (2013.01); A61K 47/10 (2013.01); A61K 47/186 (2013.01); A61K 47/26 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 47/46 (2013.01); B29B 7/88 (2013.01); B29B 13/00 (2013.01); B29C 39/02 (2013.01); B29C 39/36 (2013.01); B29C 39/38 (2013.01); B29C 41/003 (2013.01); B29C 69/001 (2013.01); A23V 2002/00 (2013.01); B29B 2013/005 (2013.01); B29K 2105/0035 (2013.01); B29L 2007/007 (2013.01);
Abstract

An edible orally disintegrating tablet dosage form containing an unpalatable acidic active pharmaceutical ingredient, particularly ketoprofen, and an ion exchange resin as a primary taste masking agent, along with an optional alkaline agent and further optionally containing one or more secondary taste masking agents is provided. The edible orally disintegrating tablet dosage matrix is formed from at least one water soluble or miscible polymer(s). The optional secondary taste masking ingredients include one or more of flavoring agent(s), sweetener(s), cooling sensation agent(s), and taste receptor blocker(s). The inventive dosages minimize or completely mask the bitterness, burning sensation and throat irritation associated with many acidic active pharmaceutical ingredients. Methods for preparing the inventive edible oral film strip dosage forms are disclosed, as well as their method of administration.


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