The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Mar. 24, 2016
Applicants:

Jsr Corporation, Minato-ku, JP;

Jsr Life Sciences Corporation, Minato-ku, JP;

Inventors:

Jun-ichi Yasuoka, Minato-ku, JP;

Takashi Ichii, Minato-ku, JP;

Satoshi Nakamura, Minato-ku, JP;

Tomonori Shiotani, Minato-ku, JP;

Kaori Itaya, Minato-ku, JP;

Assignees:

JSR CORPORATION, Minato-ku, JP;

JSR LIFE SCIENCES CORPORATION, Minato-ku, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01); C07K 1/22 (2006.01); C07K 14/195 (2006.01); C07K 17/04 (2006.01); C12N 15/09 (2006.01); C12N 5/10 (2006.01); G01N 33/68 (2006.01); C07K 16/12 (2006.01); C07K 17/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/195 (2013.01); C07K 1/22 (2013.01); C07K 14/31 (2013.01); C07K 16/1203 (2013.01); C07K 17/04 (2013.01); C07K 17/08 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); G01N 33/6854 (2013.01);
Abstract

Provided is an affinity chromatography carrier that maintains high immunoglobulin-binding capacity and high alkali resistance. An immunoglobulin-binding protein including at least one modified immunoglobulin-binding domain, the modified immunoglobulin-binding domain being a polypeptide consisting of an amino acid sequence of an immunoglobulin-binding domain selected from the group consisting of the B domain, Z domain, C domain, and variants thereof ofprotein A, in which at least one amino acid residue is inserted between positions corresponding to the 3-position and position 4 of the amino acid sequence of the B domain, Z domain or C domain.


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