The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Oct. 18, 2016
Applicant:
Cardioxyl Pharmaceuticals, Inc., Chapel Hill, NC (US);
Inventors:
Vincent Jacob Kalish, Annapolis, MD (US);
Lisa Marie Frost, Abingdon, GB;
Frederick Arthur Brookfield, Abingdon, GB;
Stephen Martin Courtney, Abingdon, GB;
Carl Leslie North, Abingdon, GB;
Matthew Robert Conroy, Abingdon, GB;
Assignee:
Cardioxyl Pharmaceuticals, Inc., Chapel Hill, NC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/46 (2006.01); C07D 231/54 (2006.01); C07D 491/048 (2006.01); C07D 491/052 (2006.01); C07D 498/04 (2006.01); A61K 31/416 (2006.01); A61K 31/4162 (2006.01); C07D 231/22 (2006.01); C07D 401/04 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/10 (2006.01); C07D 498/18 (2006.01);
U.S. Cl.
CPC ...
C07D 231/22 (2013.01); C07D 231/46 (2013.01); C07D 231/54 (2013.01); C07D 401/04 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01); C07D 498/04 (2013.01); C07D 498/10 (2013.01); C07D 498/18 (2013.01);
Abstract
The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.