The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2020

Filed:

Sep. 03, 2019
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Daniel Garrido, Santiago, CL;

J. Bruce German, Davis, CA (US);

Carlito B. Lebrilla, Davis, CA (US);

David A. Mills, Davis, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/34 (2006.01); C12N 9/24 (2006.01); C12P 21/00 (2006.01); C12P 19/04 (2006.01); A61K 38/47 (2006.01); A61K 31/715 (2006.01); A23C 9/12 (2006.01); A23L 2/52 (2006.01); A23L 33/195 (2016.01); A61K 35/741 (2015.01); A61K 38/40 (2006.01); C07K 14/79 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A23C 9/1216 (2013.01); A23L 2/52 (2013.01); A23L 33/195 (2016.08); A61K 31/715 (2013.01); A61K 35/741 (2013.01); A61K 38/40 (2013.01); C07K 14/79 (2013.01); C12N 9/2402 (2013.01); C12N 9/2497 (2013.01); C12P 19/04 (2013.01); C12P 21/005 (2013.01); A61K 38/00 (2013.01); C12Y 302/01096 (2013.01); Y02P 20/52 (2015.11);
Abstract

Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.


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