The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2020
Filed:
Dec. 03, 2015
Danisco Us Inc., Palo Alto, CA (US);
Cristina Bongiorni, Fremont, CA (US);
Rodante Gonzales Caguiat, Santa Clara, CA (US);
Carol Marie Fioresi, Redwood City, CA (US);
Brian F. Schmidt, Half Moon Bay, CA (US);
Anita Van Kimmenade, Woodside, CA (US);
Chao Zhu, Mountain View, CA (US);
DANISCO US INC, Palo Alto, CA (US);
Abstract
The present invention relates in general to bacterial cells having genetic alterations that result in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include altered Gram positive microorganisms having one or more a genetic alterations that reduce the expression of a gene in the sin operon, thereby resulting in the enhanced expression of one or more proteins of interest.