The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2020
Filed:
Oct. 21, 2016
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Benjamin F. Cravatt, La Jolla, CA (US);
Keriann M. Backus, La Jolla, CA (US);
Bruno E. Correia, La Jolla, CA (US);
Megan M. Blewett, San Diego, CA (US);
John R. Teijaro, San Diego, CA (US);
Assignee:
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C40B 60/00 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12N 9/64 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6845 (2013.01); C12N 9/0006 (2013.01); C12N 9/1007 (2013.01); C12N 9/6472 (2013.01); C12Y 101/01042 (2013.01); C12Y 201/01023 (2013.01); C12Y 304/22061 (2013.01); C12Y 304/22063 (2013.01); G01N 33/5005 (2013.01); G01N 33/5008 (2013.01); G01N 33/6842 (2013.01);
Abstract
Disclosed herein are methods, compositions, probes, polypeptides, assays, and kits for identifying a cysteine containing protein as a binding target for a small molecule fragment. Also disclosed herein are methods, compositions, and probes for mapping a biologically active cysteine site on a protein and screening a small molecule fragment for interaction with a cysteine containing protein.