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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10668048 B1

PDFFull Text
Date of Patent:
Jun. 02, 2020

Filed:

Jul. 27, 2018

Compounds for inhibiting bacterial growth via phosphatidylglycerol binding

Applicant:

Wichita State University, Wichita, KS (US);

Inventors:

Dennis H. Burns, Wichita, KS (US);

Douglas S. English, Derby, KS (US);

Assignee:

Wichita State University, Wichita, KS (US);

Attorney:

Hovey Williams LLP

Primary Examiner:

Jean P Cornet

Int. Cl.
CPC ...
A61K 31/407 (2006.01); C07D 487/22 (2006.01); A01N 43/90 (2006.01); C07D 273/08 (2006.01); C07D 321/00 (2006.01); A01N 43/72 (2006.01); A01N 43/22 (2006.01); A61P 31/04 (2006.01); A61K 31/357 (2006.01); A61K 31/395 (2006.01);
U.S. Cl.
CPC ...
A61K 31/407 (2013.01); A01N 43/22 (2013.01); A01N 43/72 (2013.01); A01N 43/90 (2013.01); A61K 31/357 (2013.01); A61K 31/395 (2013.01); A61P 31/04 (2018.01); C07D 273/08 (2013.01); C07D 321/00 (2013.01); C07D 487/22 (2013.01);
Abstract

Antibacterial small molecule compounds, termed liptins, bind to phosphatidylglycerol in bacterial plasma membranes. The small molecule compounds comprise a three-dimensional complementary binding pocket for phosphatidylglycerol, disrupting membrane function in a bacteriostatic or bactericidal manner. Methods of inhibiting bacterial growth and/or treating Gram-positive or Gram-negative bacterial infection using such compounds are also disclosed.

Find Patent Forward Citations

Burns, Dennis. (2020). Compounds for inhibiting bacterial growth via phosphatidylglycerol binding (U.S. Patent No. 10668048). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10668048

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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