The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Feb. 13, 2015
Applicant:

Ecole Polytechnique Federale DE Lausanne (Epfl), Lausanne, CH;

Inventors:

Jiandong Feng, Hangzhou, CN;

Ke Liu, Chavannes-prés-Renens, CH;

Aleksandra Radenovic, St. Sulpice, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/487 (2006.01); C12Q 1/6869 (2018.01); G01N 27/447 (2006.01); G01N 15/10 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C12Q 1/6869 (2013.01); G01N 15/1031 (2013.01); G01N 27/44791 (2013.01); G01N 2015/0065 (2013.01);
Abstract

Molecular sensing system including: a sensing device () comprising at least one support layer (), and an active layer () mounted on said support layer and having at least one nano-pore () configured for translocation of a molecular analyte () therethrough; an electrically conducting liquid () in contact with the active layer in a region around said nano-pore; and a signal processing circuit () comprising an ionic current circuit () configured to generate and measure an ionic current (Ii) in the electrically conducting liquid influenced by the translocation of the molecular analyte through the nano-pore. The molecular sensing device of the invention allows for single-nucleotide discrimination and detection of the specific sequence within ssDNA.


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