The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Dec. 12, 2006
Applicants:

James Eberwine, Philadelphia, PA (US);

Philip G. Haydon, Narberth, PA (US);

Jai-yoon Sul, Bensalem, PA (US);

Hajime Takano, Lawrenceville, NJ (US);

Chia-wen Kitty Wu, Philadelphia, PA (US);

Fanyi Zeng, Philadelphia, PA (US);

Inventors:

James Eberwine, Philadelphia, PA (US);

Philip G. Haydon, Narberth, PA (US);

Jai-Yoon Sul, Bensalem, PA (US);

Hajime Takano, Lawrenceville, NJ (US);

Chia-Wen Kitty Wu, Philadelphia, PA (US);

Fanyi Zeng, Philadelphia, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); C09K 3/00 (2006.01); A61K 48/00 (2006.01); C12N 15/10 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0083 (2013.01); C12N 13/00 (2013.01); C12N 15/1079 (2013.01); C12N 15/87 (2013.01);
Abstract

The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the transfected cell.


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