The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Nov. 16, 2016
Centre National DE LA Recherche Scientifique, Paris, FR;
Boris Vauzeilles, Sceaux, FR;
Aurélie Baron, L'Isle Adam, FR;
Jordi Mas Pons, Barecelone, ES;
Laura Fourmois, Buchelay, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
Abstract
Disclosed is a method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy--mannose. This method includes the chemical reaction of compound of formula X: Wherein: Rcan be a Cto Calkyl including methyl, ethyl, isopropyl; aryl including phenyl; each of these groups being substituted or not; and Rcan be a Cto Calkyl including methyl, ethyl, isopropyl, tert-butyl, isobutyl; each of these groups being substituted or not; with a deprotecting reagent including a Lewis or Brönsted acid in a polar aprotic solvent, thereby obtaining a free C-1 OH group. The method can also start with the preparation from commercially available-galactose pentaacetate,-galactose tetraacetate or tetraacetyl-galactosyl trichloroacetimidate. The step of deprotecting the anomeric position avoids the use of cerium and allows the easy purification of 6-azido-2,4-diacetamido-2,4,6-trideoxy--mannose.