The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Aug. 15, 2016
Applicants:
Cathay Biotech Inc., Shanghai, CN;
Cibt America Inc., Newark, DE (US);
Inventors:
Howard Chou, Shanghai, CN;
Xiucai Liu, Shanghai, CN;
Assignees:
Cathay Biotec Inc., Shanghai, CN;
CIBT America Inc., Newark, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12P 13/08 (2006.01); C12N 15/52 (2006.01); C12P 13/00 (2006.01); C07K 14/195 (2006.01); C12N 1/20 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01); C12R 1/15 (2006.01); C12R 1/19 (2006.01);
U.S. Cl.
CPC ...
C12P 13/08 (2013.01); C07K 14/195 (2013.01); C12N 1/20 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12N 15/74 (2013.01); C12P 13/001 (2013.01); C12R 1/15 (2013.01); C12R 1/19 (2013.01); C12N 2510/02 (2013.01); C12Y 401/01018 (2013.01);
Abstract
Provided herein is a genetically modified host cell comprising a heterologous nucleic acid encoding a biofilm dispersal polypeptide that decreases intracellular c-di-GMP levels and enhances the production of lysine and lysine derivatives. Further provided are methods of generating such cell and producing lysine and lysine derivatives using the genetically modified host cell.