The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2020

Filed:

Dec. 11, 2017
Applicant:

Hayashibara Co., Ltd., Okayama-Shi, Okayama, JP;

Inventors:

Takashi Shibuya, Okayama, JP;

Seisuke Izawa, Okayama, JP;

Tomoyuki Nishimoto, Okayama, JP;

Shigeharu Fukuda, Okayama, JP;

Toshio Miyake, Okayama, JP;

Assignee:

HAYASHIBARA CO., LTD., Okayama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/60 (2006.01); C07H 17/04 (2006.01); A61K 31/7048 (2006.01); C12P 19/18 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 9/16 (2013.01); C07H 17/04 (2013.01); C12P 19/18 (2013.01); C12P 19/60 (2013.01); C12Y 204/01019 (2013.01);
Abstract

The invention provides a process for enabling the production of a particulate composition containing anhydrous crystalline ascorbic acid 2-glucoside that does not significantly cake even when the production yield of ascorbic acid 2-glucoside does not reach 35% by weight. The process for producing a particulate composition containing anhydrous crystalline ascorbic acid 2-glucoside, which comprises allowing a CGTase to act on a solution containing either liquefied starch or dextrin and L-ascorbic acid and then allowing a glucoamylase to act on the resulting solution to obtain a solution with an ascorbic acid 2-glucoside production yield of at least 27%, purifying the obtained solution to increase the ascorbic acid 2-glucoside content to a level of over 86% by weight, precipitating anhydrous crystalline ascorbic acid 2-glucoside by a controlled cooling method or pseudo-controlled cooling method, collecting the precipitated anhydrous crystalline ascorbic acid 2-glucoside, and ageing and drying the collected anhydrous crystalline ascorbic acid 2-glucoside.


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