The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2020

Filed:

Aug. 28, 2017
Applicant:

Advanced Bionutrition Corporation, Columbia, MD (US);

Inventors:

Moti Harel, Pikesville, MD (US);

Qiong Tang, Columbia, MD (US);

Trisha Rice, Columbia, MD (US);

Kimberly Jennings, Laurel, MD (US);

Brian Carpenter, Baltimore, MD (US);

Roger Drewes, Hockessin, DE (US);

Elizabeth Raditsis, Columbia, MD (US);

January Scarbrough, Silver Spring, MD (US);

Assignee:

Advanced BioNutrition Corp., Columbia, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A23L 33/135 (2016.01); A61K 47/40 (2006.01); A23L 33/15 (2016.01); A23L 33/125 (2016.01); A23K 10/18 (2016.01); A23K 50/40 (2016.01); A23K 20/174 (2016.01); A23K 20/147 (2016.01); A23L 33/19 (2016.01); A23L 33/18 (2016.01); A23L 33/14 (2016.01); A23L 33/105 (2016.01); A61K 9/19 (2006.01); A01N 25/22 (2006.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01); A61K 47/26 (2006.01); A01C 1/06 (2006.01); A23K 20/163 (2016.01);
U.S. Cl.
CPC ...
A23L 33/135 (2016.08); A01C 1/06 (2013.01); A01N 25/22 (2013.01); A23K 10/18 (2016.05); A23K 20/147 (2016.05); A23K 20/163 (2016.05); A23K 20/174 (2016.05); A23K 50/40 (2016.05); A23L 33/105 (2016.08); A23L 33/125 (2016.08); A23L 33/14 (2016.08); A23L 33/15 (2016.08); A23L 33/18 (2016.08); A23L 33/19 (2016.08); A61K 9/19 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61K 47/40 (2013.01); A61K 47/42 (2013.01); A23V 2002/00 (2013.01);
Abstract

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.


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