The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Mar. 03, 2016
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Sean S. Gant, Elkton, VA (US);
Michael J. Iammarino, Kenilworth, NJ (US);
Kristi Kerchner, Elkton, VA (US);
Michael A. Rauscher, Kenilworth, NJ (US);
David J. Roush, Kenilworth, NJ (US);
Christopher H. Smith, Miami, FL (US);
Martin Chandler, Palo Alto, CA (US);
Matthew Petroff, Baltimore, MD (US);
Sean S. Gant, Elkton, VA (US);
Michael J. Iammarino, Kenilworth, NJ (US);
Kristi Kerchner, Elkton, VA (US);
Michael A. Rauscher, Kenilworth, NJ (US);
David J. Roush, Kenilworth, NJ (US);
Christopher H. Smith, Miami, FL (US);
Martin Chandler, Palo Alto, CA (US);
Matthew Petroff, Baltimore, MD (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The use of two tandem microfiltration (MF) steps in a process for making recombinant insulin is described. The two MF steps in a single downstream purification unit operation reduce both soluble and insoluble impurities and exchange the insulin product into a suitable buffer for downstream purification.