The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Sep. 04, 2018
Applicant:
Academisch Ziekenhuis Leiden H.o.d.n. Lumc, Leiden, NL;
Inventors:
Leendert Adrianus Trouw, Leiden, NL;
Reinaldus Everardus Maria Toes, Leiden, NL;
Thomas Willem Johannes Huizinga, Leiden, NL;
Petrus Antonius van Veelen, Leiden, NL;
Anthony Cerami, Leiden, NL;
Jing Shi, Leiden, NL;
Assignee:
Academisch Ziekenhuis Leiden H.O.D.N. LUMC, Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/564 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); G01N 33/6854 (2013.01); G01N 2333/75 (2013.01); G01N 2440/00 (2013.01); G01N 2800/101 (2013.01); G01N 2800/102 (2013.01); G01N 2800/104 (2013.01); G01N 2800/105 (2013.01); G01N 2800/107 (2013.01); G01N 2800/50 (2013.01); Y02A 50/57 (2018.01);
Abstract
Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-CarP) for the classification of individuals suffering from, or at risk of suffering from, arthritis.