The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2019

Filed:

Nov. 21, 2018
Applicant:

Amyris, Inc., Emeryville, CA (US);

Inventors:

Jessica Walter, Albany, CA (US);

Joshua A. Lerman, Emeryville, CA (US);

Michael Leavell, Emeryville, CA (US);

Benjamin Yap, Emeryville, CA (US);

Assignee:

Amyris, Inc., Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/12 (2006.01); C12N 15/81 (2006.01); C07H 13/04 (2006.01); C12N 9/10 (2006.01); C12N 9/24 (2006.01); C12N 9/12 (2006.01); C12N 9/88 (2006.01);
U.S. Cl.
CPC ...
C12P 19/12 (2013.01); C07H 13/04 (2013.01); C12N 9/1059 (2013.01); C12N 9/1081 (2013.01); C12N 9/1205 (2013.01); C12N 9/1241 (2013.01); C12N 9/2402 (2013.01); C12N 9/88 (2013.01); C12N 15/81 (2013.01); C12Y 204/01029 (2013.01); C12Y 204/01069 (2013.01); C12Y 204/01086 (2013.01); C12Y 204/01146 (2013.01); C12Y 204/99001 (2013.01); C12Y 207/07023 (2013.01); C12Y 207/07038 (2013.01); C12Y 207/07043 (2013.01); C12Y 302/01023 (2013.01); C12Y 302/01038 (2013.01); C12Y 302/01183 (2015.07); C12Y 402/01047 (2013.01);
Abstract

Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides. The yeast cells include one or more heterologous nucleic acids that encode enzymes of a human milk oligosaccharide biosynthetic pathway. The yeast cells do not include a heterologous nucleic acid encoding a fucokinase. Also provided are fermentation compositions including the disclosed genetically modified yeast cells, and related methods of producing and recovering human milk oligosaccharides generated by the yeast cells.


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