The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2019

Filed:

Nov. 13, 2017
Applicant:

New Jersey Institute of Technology, Newark, NJ (US);

Inventors:

Eon Soo Lee, Tenafly, NJ (US);

Bharath Babu Nunna, Randolph, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); G01N 33/574 (2006.01); G01N 27/22 (2006.01); G01N 33/545 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54373 (2013.01); B01L 3/502715 (2013.01); B01L 3/502753 (2013.01); G01N 27/226 (2013.01); G01N 27/227 (2013.01); G01N 33/545 (2013.01); G01N 33/5438 (2013.01); G01N 33/574 (2013.01); B01L 3/502746 (2013.01); B01L 2200/12 (2013.01); B01L 2200/143 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0896 (2013.01); B01L 2300/16 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0409 (2013.01); G01N 2600/00 (2013.01);
Abstract

Molecularly Imprinted Polymers (MIPs) are utilized to detect diseases and minimize false negative/positive scenarios. MIPs are implemented on a nano-electric circuit in a biochip where interactions of MIPs and an Antigen/Antibody (AG/AB) are detected, and disease specific biomarkers diagnosed. Biomarker detection is achieved with interdigitated gold electrodes in a biochip's microchannel. Capacitance changes due to biomarker interaction with AG/AB electrode coating diagnose diseases in a microfluidic environment. Biofluid passes through the microchannel and exposed to the nanocircuit to generate a capacitance difference and diagnose any specific disease in the biofluid sample. Blood capillary flow in a microchannel curved section experience centrifugal forces that separate liquid from solid. Various blood densities and segments experience different centrifugal effects while flowing through the curved section so serum is separated from various solid matter without using external devices.


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