The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Mar. 18, 2016
Applicant:
William Marsh Rice University, Houston, TX (US);
Inventors:
Assignee:
William Marsh Rice University, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12P 7/64 (2006.01); C12N 9/16 (2006.01); C12N 9/42 (2006.01); C12N 15/52 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
C12P 7/6409 (2013.01); C12N 9/16 (2013.01); C12N 9/2442 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12Y 301/02014 (2013.01); C12Y 302/01014 (2013.01); Y02P 20/52 (2015.11);
Abstract
There is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity.