The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Oct. 09, 2018
Applicant:
Shanghai Xunhe Pharmaceutical Technology Co. Ltd., Shanghai, CN;
Inventors:
Yongyong Zheng, Shanghai, CN;
Hua Jin, Shanghai, CN;
Feng Zhou, Shanghai, CN;
Meihua Huang, Shanghai, CN;
Xin Meng, Beijing, CN;
Assignee:
Shanghai Xunhe Pharmaceutical Technology Co. Ltd., Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 239/42 (2006.01); C07D 401/14 (2006.01); C07D 473/00 (2006.01); C07D 487/04 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01); C07D 473/00 (2013.01); C07D 487/04 (2013.01);
Abstract
The present disclosure relates to a 2,4-disubstituted pyrimidine derivative and the use thereof as a therapeutically effective cyclin-dependent kinase (CDK) inhibitor. In particular, the present disclosure relates to the use of a new 2,4-disubstituted pyrimidine derivatives shown in formula (I) and a pharmaceutical composition thereof as a selective CDK4/6 inhibitor in preventing or treating diseases related to CDK4/6.