The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Jul. 20, 2015
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Gordon M. Cann, Redwood City, CA (US);

Jeffrey G. Mandell, La Jolla, CA (US);

Alex Aravanis, San Mateo, CA (US);

Steven Norberg, San Diego, CA (US);

Dmitry K. Pokholok, San Marcos, CA (US);

Frank J. Steemers, Encinitas, CA (US);

Farnaz Absalan, San Francisco, CA (US);

Leila Bazargan, Palo Alto, CA (US);

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12N 15/10 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/683 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C12N 15/102 (2013.01); C12Q 1/683 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6869 (2013.01); C12Q 2521/301 (2013.01);
Abstract

A method for enriching a target nucleic acid comprising providing an endonuclease system having a crRNA or a derivative thereof, and a Cas protein or a variant thereof. The crRNA or the derivative thereof contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid; contacting the target nucleic acid with the endonuclease system to form a complex; and separating the complex and thereby enriching for the target nucleic acid.


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