The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Aug. 02, 2013
Applicants:
Novartis Ag, Basel, CH;
Massachusetts Institute of Technology (Mit), Cambridge, MA (US);
Inventors:
Neeraj J. Agrawal, Cambridge, MA (US);
Bernhard Helk, Basel, CH;
Bernhardt L. Trout, Cambridge, MA (US);
Assignees:
NOVARTIS AG, Basel, CH;
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MIT), Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 15/00 (2019.01); G16B 35/00 (2019.01); G16B 5/00 (2019.01); G16C 20/60 (2019.01); C07K 1/107 (2006.01);
U.S. Cl.
CPC ...
G16B 15/00 (2019.02); C07K 1/107 (2013.01); G16B 35/00 (2019.02); G16C 20/60 (2019.02); G16B 5/00 (2019.02);
Abstract
The present disclosure relates to methods and computational tools based, at least in part, on computer simulations that identify hot-spot amino acid residues and binding-region amino acid residues of a protein.