The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Dec. 11, 2014
Applicant:

Dsm Ip Assets B.v., Heerlen, NL;

Inventors:

Maaike Johanna Bruins, Delft, NL;

Luppo Edens, Delft, NL;

Helena Maria Nan, Delft, NL;

Assignee:

DSM IP ASSETS B.V., Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A23L 5/20 (2016.01); A23L 29/00 (2016.01); A21D 8/04 (2006.01); A61K 9/00 (2006.01); C12N 9/62 (2006.01); C12C 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/488 (2013.01); A21D 8/042 (2013.01); A23L 5/25 (2016.08); A23L 29/06 (2016.08); A61K 9/0053 (2013.01); A61K 38/482 (2013.01); C12C 5/004 (2013.01); C12N 9/62 (2013.01); C12Y 304/21026 (2013.01); C12Y 304/23018 (2013.01); C12Y 304/23019 (2013.01); A23V 2002/00 (2013.01);
Abstract

This invention relates to a medicament or a dietary supplement comprising theaspergilloglutamic peptidase that is capable of hydrolyzing plant food allergens, and more particularly, alpha-amylase/trypsin inhibitors, thereby treating diseases due to an innate immune response in humans, and/or allowing to delay the onset of said diseases. The present invention relates to the discovery that theaspergilloglutamic peptidase is capable of hydrolyzing alpha-amylase/trypsin inhibitors that are present in wheat and related cereals said inhibitors being strong inducers of innate immune response. Furthermore, the present invention relates to a method for hydrolyzing alpha-amylase/trypsin inhibitors comprising incubating a composition for food consumption comprising alpha-amylase/trypsin inhibitors with theaspergilloglutamic peptidase, wherein the inhibitors are hydrolyzed. It also relates to an enzyme composition comprising theaspergilloglutamic peptidase and an additional enzyme, and to foodstuff comprising theaspergilloglutamic peptidase.


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